Dupuytren's disease & drug repurposing
Where research should go next
Twelve specific projects that would move this field forward, each with the skills and effort it needs.
Why it’s usefulIf you're a researcher, clinician or funder, this is the list I'd work from. Some are small jobs a single person could do.
Start here
Two problems hold back every candidate at once: nobody knows how often untreated early disease progresses (OP_01), and the only positive drug trial used an endpoint that hasn't been validated (OP_02). A better way of measuring hand function could help with both: see Measuring outcomes.
Effort
Working on one of these, or know a study that already answers it? Get in touch (willshawphd@gmail.com).